Four highly-interdependent Working Groups (WGs) were formed at the start of the Action to update, discuss and bring forward those important topics in ME research, as detailed in the associated Tasks.All participants of the Action will be invited to join at least one of the WGs, depending on their research interests. The WGs will meet twice per year, if funds allow, and the first meeting every year will be combined with the MC meeting.

Additionally meetings, when relevant, will be through teleconference, Skype or a similar means of communication. The Action will combine these WG meetings as participants will typically work on more than one aspect (i.e. more than one WG) and isolated meetings would hinder scientific exchange.